Our work in this area explores how to enable global conversations about racism as a fundamental step toward its eradication. Major challenges to eliminating racism include countering its silencing, breaking down silos of exceptionalism, shifting the focus from identity politics to systemic inequality and moving from the distribution of disadvantage to the accumulation of privilege. Addressing these challenges requires re-orienting analytical frameworks, developing agile and flexible conceptual tools, and fostering dialogues across parallel global processes.